KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PCNA
All Species:
48.48
Human Site:
Y239
Identified Species:
82.05
UniProt:
P12004
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P12004
NP_002583.1
261
28769
Y239
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_534355
466
50130
Y444
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Cat
Felis silvestris
Mouse
Mus musculus
P17918
261
28766
Y239
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Rat
Rattus norvegicus
P04961
261
28730
Y239
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q9DEA3
262
28869
Y239
D
V
P
L
V
V
E
Y
K
I
A
D
M
G
H
Frog
Xenopus laevis
P18248
261
28878
Y239
D
I
P
L
V
V
E
Y
K
I
A
D
M
E
H
Zebra Danio
Brachydanio rerio
Q9PTP1
260
28592
Y239
D
I
P
L
V
V
E
Y
K
I
A
D
M
G
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17917
260
28812
Y239
D
V
P
L
V
V
E
Y
A
I
K
D
L
G
H
Honey Bee
Apis mellifera
XP_001122985
261
29111
Y239
D
V
P
L
V
C
E
Y
K
I
G
D
I
G
H
Nematode Worm
Caenorhab. elegans
O02115
229
25366
I208
P
V
V
V
E
Y
P
I
E
E
N
G
Y
L
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
XP_002313402
264
29135
Y239
D
L
P
V
V
V
E
Y
K
I
A
E
M
G
Y
Maize
Zea mays
Q43266
263
29324
Y239
E
L
P
V
V
V
E
Y
K
I
A
E
M
G
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9ZW35
264
29204
Y239
E
L
P
V
V
V
E
Y
K
V
A
E
M
G
Y
Baker's Yeast
Sacchar. cerevisiae
P15873
258
28898
F237
S
S
E
A
P
A
L
F
Q
F
D
L
K
S
G
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
55.7
N.A.
96.9
98.4
N.A.
N.A.
94.2
89.2
91.9
N.A.
70.5
62.4
40.2
N.A.
Protein Similarity:
100
N.A.
N.A.
55.7
N.A.
98.4
99.2
N.A.
N.A.
97.3
96.1
95.7
N.A.
85.8
81.9
62.8
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
86.6
93.3
N.A.
80
80
6.6
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
100
100
N.A.
N.A.
100
93.3
100
N.A.
86.6
86.6
20
N.A.
Percent
Protein Identity:
65.9
61.9
N.A.
64.7
35.2
N.A.
Protein Similarity:
84
82.5
N.A.
85.2
62.4
N.A.
P-Site Identity:
73.3
66.6
N.A.
60
0
N.A.
P-Site Similarity:
100
100
N.A.
100
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
8
0
0
8
0
72
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% C
% Asp:
72
0
0
0
0
0
0
0
0
0
8
65
0
0
0
% D
% Glu:
15
0
8
0
8
0
86
0
8
8
0
22
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
8
0
79
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
65
% H
% Ile:
0
15
0
0
0
0
0
8
0
79
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
79
0
8
0
8
0
0
% K
% Leu:
0
22
0
65
0
0
8
0
0
0
0
8
8
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
72
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
0
86
0
8
0
8
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% R
% Ser:
8
8
0
0
0
0
0
0
0
0
0
0
0
8
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
58
8
29
86
79
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
86
0
0
0
0
8
0
22
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _